Shrinkage of under chin area after one session of Kybella.
Results may vary for different people.

Kybella (deoxycholate)

In 2015, the FDA approved Kybella (deoxycholate) as an injectable compound to shrink moderate to severe under the chin, and upper neck fullness and laxity. Deoxycholate precursor is a compound that our liver produces to be poured in the upper portion of the small intestine to digest fat. Prior to 2015, for many years, deoxycholate was injected by healthcare providers as mesotherapy to shrink fatty tissue in various parts of the body.

Deoxycholate emulsifies (solubilizes) fat molecules. The cell wall of all of our cells contain fat. As you are aware, much of the content of fat cells is fat. When the cell membrane, and the content of the fat cells are disrupted, the cell dies. The ensuing gathering of the immune cells to digest away the remnant of the damaged cells results in fibrosis, or microscopic scar formation.

Kybella is FDA approved to be injected under the chin, where it is primarily populated with fat cells, and far from vital organs. Inadvertent injection, or diffusion of deoxycholate into non-fat cells, does not result in irreversible loss or damage.

What Is Involved in Kybella Treatment?

The boundaries of where it would be safe to inject Kybella is drawn under the chin. Small amounts of the clear fluid that contains deoxycholate is injected about 1/4 of an inch deep from the surface of the skin, where it is populated with fat cells.

Is the Treatment Painful?

Shortly after the solution is introduced into the skin the patient feels a tolerable local heat sensation. Most patients can tolerate the procedure without prior lidocaine injection. If a patient requests, Dr. Silvers would inject the area with lidocaine beforehand. Placement of a cold pack eases the discomfort quite a bit. The heat sensation lasts for a few minutes. Thereafter, minimal to mild soreness is the most some patients report.

What Is to Be Expected After the Treatment?

It is now believed among doctors that the recommended dose must be injected to be able to expect noticeable shrinkage of the fullness under he chin. Injection of the recommended dose results in marked swelling of the area for three days, and decreasing from then on. After a week, most, if not all, the patients are presentable, although the area still remains somewhat puffy over the first seven days after he injection. Patients are asked to massage the area daily on that first week after the treatment. Patients report a crackling feeling when they massage the area. No redness, discharge or wound is expected. The shrinkage will be noted in six to eight weeks, after six weeks of disappointment. In the great majority of cases, the shrinkage is not appreciable after the first session, unless when the before-and-after photographs are compared.

How Long of A Gap Is There Supposed to Be in Between Kybella Treatments?

When it has been a few weeks after a treatment session that the patient no longer notes any further change or shrinkage, which is usually about six to twelve weeks after a treatment, it would be time to repeat it. Only if the patient wishes to note further shrinkage of the site, another round of treatment can be done.

Can Kybella Be Injected At Other Sites Besides Under the Chin?

It sure can be injected at any site that is primarily made up of fat cells. Similar healing phase with a week long swelling can be expected. The cost can be prohibitive for wide areas.

Who Should Avoid Kybella Treatment?

  • People with weakened immune system,
  • Diabetic patients
  • Patients with neurological disorders, such as multiple sclerosis

Kybella is good for those candidates who:

  • Have reasonable expectations/li>

What Are the Possible Risks Associated With Kybella Treatment?

Almost all patients notice some numbness under he chin, where Kybella was injected. The numbness lasts for a few weeks, and eventually wears off. Very rarely, the nerve that innervates the muscles of the lower lip can affected, resulting in the dysfunction of the lower lip. All the patients that have experienced this side effect have fully recovered.

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